Pramin 25mg (Tablet)
Manufactured by: Incepta Pharmaceuticals Ltd.
Imipramine Hydrochloride Similar medicine
Pramin is indicated for
- 憂鬱症、夜間遺尿
Precautions and warnings
丙咪嗪應在醫生的密切監督下謹慎使用，尤其是老年人和患有前列腺肥大、排尿困難或青光眼（尤其是閉角型青光眼）的患者。 如果與其他減慢大腦速度的物質（如酒精、安眠藥、其他鎮靜劑或抗組織胺）一起服用，其鎮靜（鎮靜）作用會變得更強。 丙咪嗪也會加快心跳速度，給心臟帶來額外的壓力，這對患有心臟病的人來說是危險的，尤其是最近心臟病發作的人。 老年人和患有心脏病的人可能面临心律不齐、心力衰竭、心脏病发作、心率过快或中风的风险。 開始服用丙咪嗪的人需要密切監測自殺想法，直到找到合適的劑量，因為自殺的風險可能更高，特別是如果大量服用丙咪嗪或與酒精混合服用。 开始服用丙咪嗪有时会引发躁狂发作或使现有心理健康问题的症状变得更糟。
Side-effects
- 最常見的副作用是口乾、便秘、尿滯留、心率加快、鎮靜、煩躁、頭暈和協調性下降。 如果口乾嚴重到導致說話或吞嚥困難，可以透過減少劑量或暫時停藥來控制。 丙咪嗪的使用與血壓和心率的升高和降低有關。 已有心臟病發作、充血性心臟衰竭和中風的通報。 據報道，一小部分服用丙咪嗪的人會出現混亂、迷失方向、妄想、失眠和焦慮等副作用。 與皮膚相關的問題（感覺喪失、麻木和刺痛、皮疹、斑點、搔癢和浮腫）、癲癇發作和耳鳴也有報告。 噁心、嘔吐、食慾不振、腹瀉和腹部絞痛都是與少數人使用丙咪嗪相關的副作用。
Drug Interactions
如果與奎尼丁、西咪替丁、SSRIs、普羅帕酮或氟卡尼一起服用，藥物的血漿濃度會增加。 巴比妥類藥物和苯妥英鈉可降低其血漿濃度。 該藥也可能使抗膽鹼能藥物的藥效更強。 與六甲蜜胺一起服用會導致站立時血壓嚴重下降。 將其與酒精混合會導致困倦並影響您執行任務的能力。
**危險反應：**
將這種藥物與腎上腺素、去甲腎上腺素或哌醋甲酯一起使用可能會導致危及生命的高血壓。 它可以減弱胍乙啶、倍受定、異喹啉、溴芐銨、甲基多巴和可樂定等藥物的降血壓作用。 與 MAOIs（單胺氧化酶抑制劑）一起服用可能會導致血清素症候群；這些藥物之間應該間隔 3 週。
Contraindications
丙咪嗪不應與 MAO 抑制劑同時服用，也不應在停用 MAO 抑制劑後 14 天內服用。 兩者一起服用可能會導致嚴重的問題，例如血壓非常高、極度不安、高燒、肌肉僵硬、嚴重癲癇發作、昏迷甚至死亡。
丙咪嗪不應用於有嚴重肝臟或腎臟問題、有血液疾病病史的人，或任何對丙咪嗪或類似三環抗憂鬱劑（二苯並氮雜卓類）過敏的人。 對於剛從心臟病發作中恢復的人或患有癲癇症或青光眼的人來說，它也不安全。
Mode of actions
丙咪嗪主要阻斷去甲腎上腺素的再攝取，並在較小程度上阻斷血清素的再攝取。
Dosage & Administration
憂鬱症，最初每天分次服用75毫克，逐漸增加到150-200毫克（住院患者最多300毫克）；睡前單劑量最多可服用 150 毫克；老年人最初每日10毫克，逐漸增加至每日30-50毫克；不建議患有憂鬱症的孩子。
夜間遺尿，兒童7-8歲25mg，8-11歲25-50mg，11歲以上50-75mg睡前；最大限度。 治療期（包括逐漸停藥）3個月－進一步療程前進行全面體檢。
Pregnancy & Lactation
懷孕期間不允許使用這種藥物。 如果您懷孕了，請勿使用它。 它可以透過皮膚和肺部吸收，從而損害未出生孩子的器官並導致先天性殘疾。 治療期間及停藥後六個月內嚴格有效的節育。 如果您確實懷孕了，請停止服用此藥並立即與您的醫生討論。
沒有關於這種藥物是否會進入母乳的具體資訊。 考慮到兒童可能存在的風險，不建議在使用該藥物時進行母乳喂養，並且至少在最後一次用藥後兩週進行母乳喂養。 哺乳前請先諮詢您的醫生。
Pack Size & Price
50's pack Price : ৳100
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