Topiclo-S (Ointment)
Manufactured by: Eskayef Bangladesh Ltd.
Clobetasol Propionate 0.05% + Salicylic Acid 3% Similar medicine
Topiclo-S is indicated for
- الصدفية، الحروق، حب الشباب، الأكزيما، خلل التقرن، السماك، الثآليل، فرط التقرن، الذرة، الكالس، الزهم، مرض جلدي متقشر، تساقط الشعر، تعرق القدمين، التهاب الجلد
Precautions and warnings
لا تستخدم هذا المنتج بكميات كبيرة أو على مناطق واسعة من الجسم لفترة طويلة. إذا كنت تعاني من ضعف الدورة الدموية أو مرض السكري، فكن حذرًا للغاية. لا تضعه على الجلد المكسور أو داخل الفم أو العينين أو الأغشية المخاطية أو المناطق التناسلية والشرج.
Side-effects
- الاستخدام المطول لكمية كبيرة من بروبيونات كلوبيتاسول يمكن أن يؤدي إلى مستويات جهازية كافية لإنتاج تثبيط الغدة الكظرية، ومتلازمة كوشينغ، والسكري وارتفاع ضغط الدم. ضمور الجلد والبشرة خاصة على الوجه، وفرفرية الستيرويد.
Drug Interactions
بروبيونات كلوبيتاسول: تناول هذا الدواء مع مثبطات CYP3A4 (مثل ريتونافير أو إيتراكونازول) يمكن أن يزيد من كمية كلوبيتاسول في جسمك.
Mode of actions
** الكورتيكوستيرويدات ** تقلل الالتهاب بعدة طرق. فهي تحافظ على استقرار بعض أغشية الخلايا المناعية بحيث لا يتم إطلاق الإنزيمات الضارة، وتمنع الخلايا البلعمية من التجمع في المواقع الملتهبة، وتجعل من الصعب على خلايا الدم البيضاء الالتصاق بجدران الأوعية الدموية. كما أنها تقلل من مدى سهولة تسرب السوائل من الأوعية الدموية، مما يساعد على منع التورم، كما أنها تخفض مستويات البروتينات المشاركة في الاستجابة المناعية. بالإضافة إلى ذلك، تمنع الكورتيكوستيرويدات تأثيرات الهستامين وتقلل من إطلاق الأقارب، وكلاهما متورط في الالتهاب. كما أنها تبطئ نشاط الخلايا (الخلايا الليفية) التي تنتج الكولاجين والأنسجة الندبية.
**حمض الساليسيليك** يعمل بشكل أساسي عن طريق تكسير وتنعيم الطبقة الخارجية من الجلد (الطبقة القرنية) عند تطبيقه على الجلد. فهو يزيد من رطوبة الجلد، مما يؤدي إلى انتفاخ هذه الطبقة وتنعيمها وتساقطها في النهاية. بكميات كبيرة، يمكن لحمض الساليسيليك أن يحرق الجلد بالفعل. بالإضافة إلى ذلك، فهو يتمتع بخصائص خفيفة مضادة للبكتيريا والفطريات.
Dosage & Administration
الكبار: حب الشباب الموضعي. حالات فرط التقرن وتقشر الجلد كتحضير بنسبة 2-6%: يستخدم أكثر من 3 مرات في اليوم. الثآليل ومسامير القدم كتحضير بنسبة 60%: يستخدم حسب التوجيهات.
Pregnancy & Lactation
على الرغم من أن دراسات التكاثر الحيواني أظهرت تأثيرًا سلبيًا على الجنين ولا توجد دراسات كافية ومراقبة بشكل جيد عند النساء الحوامل، إلا أنه خلال فترة الحمل، يمكن استخدام هذا الدواء فقط عندما تكون هناك حاجة إليه بالتأكيد على الرغم من المخاطر المحتملة.
نادراً ما تظهر على الأمهات اللاتي لديهن طفل حديث الولادة والذين استخدموا هذا الدواء خلال الأشهر الثلاثة الأخيرة من الحمل أعراض بما في ذلك النعاس، وتصلب العضلات أو الارتعاش، ومشاكل التغذية أو التنفس، والبكاء المستمر. إذا لاحظت أياً من هذه الأعراض لدى طفلك خاصة خلال شهره الأول، أخبري الطبيب فوراً.
ينتقل هذا الدواء إلى حليب الثدي. تحدثي مع طبيبك قبل الرضاعة الطبيعية.
Pack Size & Price
10gm tube Price : ৳70
Similar medicine
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Manufactured by: Eskayef Bangladesh Ltd.
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