Topiclo-S (Ointment)
Manufactured by: Eskayef Bangladesh Ltd.
Clobetasol Propionate 0.05% + Salicylic Acid 3% Similar medicine
Topiclo-S is indicated for
- Psoríase
- Queimaduras
- Acne vulgar
- Eczema
- Disqueratose
- Ictiose
- Verrugas
- Hiperqueratose
- Milho
- Calos
- Seborreia
- Doença de pele escamosa
- Queda de cabelo
- Sudorese nos pés
- Dermatite
Precautions and warnings
Não use este produto em grandes quantidades ou em grandes áreas do corpo por muito tempo. Se você tem má circulação sanguínea ou diabetes, tome cuidado extra. Não aplique na pele ferida, no interior da boca, nos olhos, nas mucosas ou nas áreas genital e anal.
Side-effects
- O uso prolongado de grandes quantidades de propionato de clobetasol pode levar a níveis sistêmicos suficientes para produzir supressão adrenal
- síndrome de Cushing
- diabetes e hipertensão. Atrofia dérmica e epidérmica
- especialmente na face
- púrpura esteróide
Drug Interactions
Propionato de Clobetasol: Tomar este medicamento com inibidores do CYP3A4 (como ritonavir ou itraconazol) pode aumentar a quantidade de clobetasol no seu corpo.
Mode of actions
**Corticosteróides** reduzem a inflamação de várias maneiras. Eles mantêm certas membranas de células imunológicas estáveis para que enzimas prejudiciais não sejam liberadas, impedem que os macrófagos se acumulem em locais inflamados e dificultam a adesão dos glóbulos brancos às paredes dos vasos sanguíneos. Eles também diminuem a facilidade com que o fluido vaza dos vasos sanguíneos, o que ajuda a prevenir o inchaço, e diminuem os níveis de proteínas envolvidas na resposta imunológica. Além disso, os corticosteróides bloqueiam os efeitos da histamina e reduzem a libertação de cininas, ambas envolvidas na inflamação. Eles também retardam a atividade das células (fibroblastos) que produzem colágeno e tecido cicatricial.
**O ácido salicílico** atua principalmente quebrando e suavizando a camada externa da pele (o estrato córneo) quando aplicado na pele. Aumenta a umidade da pele, o que faz com que essa camada inche, amoleça e, eventualmente, caia. Em grandes quantidades, o ácido salicílico pode queimar a pele. Além disso, possui suaves propriedades antibacterianas e antifúngicas.
Dosage & Administration
Adulto: Acne Tópica; Condições cutâneas hiperceratóticas e descamativas Como preparação de 2-6%: Aplicar >3 vezes/dia. Verrugas e calosidades Como preparação 60%: Aplicar conforme as instruções.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso no feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário, apesar dos riscos potenciais.
As mães com um bebê recém-nascido que usaram este medicamento durante os últimos 3 meses de gravidez raramente podem apresentar sintomas incluindo sonolência, rigidez ou tremores musculares, problemas de alimentação ou respiração, choro constante. Se você notar algum destes sintomas em seu bebê, especialmente durante o primeiro mês, informe o médico imediatamente.
Este medicamento passa para o leite materno. Converse com seu médico antes de amamentar.
Pack Size & Price
10gm tube Price : ৳70
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