Topiclo-S (Ointment)
Manufactured by: Eskayef Bangladesh Ltd.
Clobetasol Propionate 0.05% + Salicylic Acid 3% Similar medicine
Topiclo-S is indicated for
- सोरायसिस
- जलन
- मुँहासा
- एक्जिमा
- डिस्केरटोसिस
- इचथ्योसिस
- मस्से
- हाइपरकेराटोसिस
- कॉर्न
- कैलस
- सेबोरहिया
- पपड़ीदार त्वचा रोग
- बालों का झड़ना
- पैरों में पसीना
- त्वचाशोथ
Precautions and warnings
इस उत्पाद का उपयोग अधिक मात्रा में या लंबे समय तक शरीर के बड़े क्षेत्रों पर न करें। यदि आपको खराब रक्त परिसंचरण या मधुमेह है, तो अतिरिक्त सावधान रहें। इसे टूटी हुई त्वचा, मुंह के अंदर, आंखों, श्लेष्मा झिल्ली, या जननांग और गुदा क्षेत्रों पर न लगाएं।
Side-effects
- बड़ी मात्रा में क्लोबेटासोल प्रोपियोनेट के लंबे समय तक उपयोग से अधिवृक्क दमन
- कुशिंग सिंड्रोम
- मधुमेह और उच्च रक्तचाप उत्पन्न करने के लिए पर्याप्त प्रणालीगत स्तर हो सकता है। चेहरे पर त्वचीय और एपिडर्मल शोष
- स्टेरॉयड पुरपुरा
Drug Interactions
क्लोबेटासोल प्रोपियोनेट: इस दवा को CYP3A4 अवरोधकों (जैसे रटनवीर या इट्राकोनाज़ोल) के साथ लेने से आपके शरीर में क्लोबेटासोल की मात्रा बढ़ सकती है।
Mode of actions
**कॉर्टिकोस्टेरॉयड** कई तरीकों से सूजन को कम करता है। वे कुछ प्रतिरक्षा कोशिका झिल्लियों को स्थिर रखते हैं ताकि हानिकारक एंजाइम जारी न हों, मैक्रोफेज को सूजन वाले स्थानों पर इकट्ठा होने से रोकते हैं, और श्वेत रक्त कोशिकाओं के लिए रक्त वाहिका की दीवारों से चिपकना कठिन बना देते हैं। वे यह भी कम करते हैं कि रक्त वाहिकाओं से तरल पदार्थ कितनी आसानी से बाहर निकलता है, जो सूजन को रोकने में मदद करता है, और वे प्रतिरक्षा प्रतिक्रिया में शामिल प्रोटीन के स्तर को कम करते हैं। इसके अतिरिक्त, कॉर्टिकोस्टेरॉइड्स हिस्टामाइन के प्रभाव को रोकते हैं और किनिन की रिहाई को कम करते हैं, जो दोनों सूजन में शामिल होते हैं। वे कोलेजन और निशान ऊतक का उत्पादन करने वाली कोशिकाओं (फाइब्रोब्लास्ट) की गतिविधि को भी धीमा कर देते हैं।
**सैलिसिलिक एसिड** त्वचा पर लगाने पर मुख्य रूप से त्वचा की बाहरी परत (स्ट्रेटम कॉर्नियम) को तोड़कर और नरम करके काम करता है। यह त्वचा में नमी बढ़ाता है, जिससे यह परत सूज जाती है, मुलायम हो जाती है और अंततः झड़ जाती है। बड़ी मात्रा में, सैलिसिलिक एसिड वास्तव में त्वचा को जला सकता है। इसके अलावा इसमें हल्के एंटीबैक्टीरियल और एंटीफंगल गुण भी होते हैं।
Dosage & Administration
वयस्क: सामयिक मुँहासे; हाइपरकेराटोटिक और स्केलिंग त्वचा की स्थिति 2-6% तैयारी के रूप में: प्रति दिन 3 बार लगाएं। मस्से और कॉलस 60% तैयारी के रूप में: निर्देशानुसार लगाएं।
Pregnancy & Lactation
यद्यपि पशु प्रजनन अध्ययनों ने भ्रूण पर प्रतिकूल प्रभाव दिखाया है और गर्भवती महिलाओं में कोई पर्याप्त और अच्छी तरह से नियंत्रित अध्ययन नहीं हैं, लेकिन गर्भावस्था के दौरान, संभावित जोखिमों के बावजूद, इस दवा का उपयोग केवल तभी किया जा सकता है जब इसकी आवश्यकता हो।
जिन माताओं के नवजात शिशु हैं, जिन्होंने गर्भावस्था के आखिरी 3 महीनों के दौरान इस दवा का उपयोग किया है, उनमें शायद ही कभी उनींदापन, मांसपेशियों में अकड़न या कंपकंपी, दूध पीने या सांस लेने में परेशानी, लगातार रोना जैसे लक्षण पैदा हो सकते हैं। यदि आपको विशेष रूप से उनके पहले महीने के दौरान अपने बच्चे में इनमें से कोई भी लक्षण दिखाई देता है, तो तुरंत डॉक्टर को बताएं।
यह दवा स्तन के दूध में पारित हो जाती है। स्तनपान कराने से पहले अपने डॉक्टर से बात करें।
Pack Size & Price
10gm tube Price : ৳70
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