Topiclo-S (Ointment)
Manufactured by: Eskayef Bangladesh Ltd.
Clobetasol Propionate 0.05% + Salicylic Acid 3% Similar medicine
Topiclo-S is indicated for
- Psoriasis
- Verbrennungen
- Akne vulgaris
- Ekzeme
- Dyskeratose
- Ichthyose
- Warzen
- Hyperkeratose
- Mais
- Hornhaut
- Seborrhoe
- schuppige Hauterkrankung
- Haarausfall
- schwitzende Füße
- Dermatitis
Precautions and warnings
Verwenden Sie dieses Produkt nicht über einen längeren Zeitraum in großen Mengen oder auf großen Körperflächen. Seien Sie besonders vorsichtig, wenn Sie unter Durchblutungsstörungen oder Diabetes leiden. Tragen Sie es nicht auf verletzter Haut, im Mund, in den Augen, auf Schleimhäuten oder im Genital- und Analbereich auf.
Side-effects
- Die längere Einnahme großer Mengen Clobetasolpropionat kann zu ausreichenden systemischen Spiegeln führen
- die zu Nebennierenunterdrückung
- Cushing-Syndrom
- Diabetes und Bluthochdruck führen. Dermale und epidermale Atrophie
- insbesondere im Gesicht
- Steroidpurpura
Drug Interactions
Clobetasolpropionat: Die Einnahme dieses Medikaments zusammen mit CYP3A4-Inhibitoren (wie Ritonavir oder Itraconazol) kann die Menge an Clobetasol in Ihrem Körper erhöhen.
Mode of actions
**Kortikosteroide** reduzieren Entzündungen auf verschiedene Weise. Sie halten bestimmte Immunzellmembranen stabil, sodass schädliche Enzyme nicht freigesetzt werden, verhindern, dass sich Makrophagen an entzündeten Stellen ansammeln, und erschweren es weißen Blutkörperchen, an den Wänden der Blutgefäße zu haften. Sie verringern auch die Leichtigkeit, mit der Flüssigkeit aus den Blutgefäßen austritt, was dazu beiträgt, Schwellungen vorzubeugen, und senken die Menge an Proteinen, die an der Immunantwort beteiligt sind. Darüber hinaus blockieren Kortikosteroide die Wirkung von Histamin und reduzieren die Freisetzung von Kininen, die beide an Entzündungen beteiligt sind. Sie verlangsamen auch die Aktivität von Zellen (Fibroblasten), die Kollagen und Narbengewebe produzieren.
**Salicylsäure** wirkt hauptsächlich durch den Abbau und die Erweichung der äußeren Hautschicht (Stratum corneum), wenn sie auf die Haut aufgetragen wird. Es erhöht die Feuchtigkeit in der Haut, was dazu führt, dass diese Schicht anschwillt, weicher wird und sich schließlich ablöst. In großen Mengen kann Salicylsäure tatsächlich die Haut verbrennen. Darüber hinaus verfügt es über milde antibakterielle und antimykotische Eigenschaften.
Dosage & Administration
Erwachsene: Topische Akne; Hyperkeratotische und schuppende Hauterkrankungen. Als 2-6 %ige Zubereitung: > 3-mal täglich auftragen. Warzen und Hornhaut Als 60 %-Präparat: Nach Anweisung anwenden.
Pregnancy & Lactation
Obwohl Reproduktionsstudien an Tieren eine nachteilige Wirkung auf den Fötus gezeigt haben und es keine ausreichenden und gut kontrollierten Studien bei schwangeren Frauen gibt, kann dieses Arzneimittel trotz möglicher Risiken während der Schwangerschaft nur dann angewendet werden, wenn dies unbedingt erforderlich ist.
Bei Müttern eines Neugeborenen, die dieses Arzneimittel in den letzten drei Monaten der Schwangerschaft eingenommen haben, kann es selten zu Symptomen wie Schläfrigkeit, Muskelsteifheit oder Zittern, Schwierigkeiten beim Füttern oder Atmen und ständigem Weinen kommen. Wenn Sie eines dieser Symptome bei Ihrem Baby bemerken, insbesondere im ersten Monat, informieren Sie sofort den Arzt.
Dieses Arzneimittel geht in die Muttermilch über. Sprechen Sie vor dem Stillen mit Ihrem Arzt.
Pack Size & Price
10gm tube Price : ৳70
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