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Trazapin 15 mg (Tablet)

Manufactured by: Albion Laboratories Ltd.

Mirtazapine Similar medicine

Trazapin is indicated for

  • Depression
  • Major depressive disorder

Precautions and warnings

Epilepsy or history of seizures; avoid completely in unstable cases. Hepatic or renal impairment, cardiac disorders e.g. conduction disturbances, angina pectoris, recent MI. Hypotension, DM, psychoses, history of bipolar disorder. Stop treatment if jaundice develops. Micturition disturbances, angle-closure glaucoma, raised intraocular pressure. Monitor patient for signs of bone marrow depression. Monitor patient for suicidal tendency. Avoid abrupt withdrawal. May impair ability to drive or operate machinery. Pregnancy and lactation. Elderly.

Side-effects

  • Increase in appetite
  • wt
  • oedema; drowsiness or sedation; dizziness
  • headache
  • increased liver enzyme levels; jaundice. Orthostatic hypotension
  • rash
  • nightmares
  • agitation
  • mania
  • hallucinations
  • paraesthesia
  • convulsions
  • tremor
  • myoclonus
  • akathisia
  • restless legs syndrome
  • arthralgia
  • myalgia
  • reversible agranulocytosis
  • leucopenia
  • granulocytopenia
  • hyponatraemia.

Drug Interactions

Potentiation of sedative effects with alcohol or benzodiazepines. Increased plasma levels with potent CYP3A4 inhibitors (e.g. HIV-protease inhibitors, azole antifungals including ketoconazole, erythromycin, nefazodone). Reduced plasma levels with carbamazepine and other inducers of CYP3A4. Increased bioavailability with cimetidine.
Potentially Fatal: Do not use with or within 2 wk of stopping an MAOI; at least 1 wk should elapse between discontinuing mirtazapine and initiating any drug which may provoke a serious reaction (e.g. phenelzine).

Contraindications

Mirtazapine Tablets are contraindicated in patients with a known hypersensitivity to mirtazapine or to any of the excipients.

Mode of actions

Mirtazapine, a piperazinoazepine tetracyclic antidepressant, enhances noradrenergic and serotonergic activity through blockade of central presynaptic adrenergic ?2-receptors.

Dosage & Administration

Adult: PO Initial: The recommended starting dose for (mirtazapine) Tablets is 15 mg/day, administered in a single dose, preferably in the evening prior to sleep. In the treatment of major depressive disorder, the effective dose range was generally 15-45 mg/day as 1-2 divided doses.

Pregnancy & Lactation

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pack Size & Price

100's pack Price : ৳

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There are some similar medicines of Trazapin are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

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