Pronapen 8 LAC (Injection)
Manufactured by: Renata Limited
Benzyl Penicillin + Procaine Penicillin Similar medicine
Pronapen 8 LAC is indicated for
- التهاب السحايا، التهاب الصفاق، الجمرة الخبيثة، التهاب الإحليل غير السيلاني، الخناق، الزهري، الالتهابات التي تسببها المكورات العنقودية (السلالات الحساسة)، المكورات العقدية، أنواع المكورات الرئوية السيلان، التهاب الشغاف البكتيري تحت الحاد، الجهاز التنفسي العلوي، الحمرة، التهابات الجلد والأنسجة الرخوة، الالتهاب الرئوي والتهاب الأذن الوسطى الشديد إلى حد ما، الدبيلة، تجرثم الدم، التهاب التامور، التهاب المفاصل
Precautions and warnings
ينبغي تناول البنسلين بحذر عند الأشخاص الذين لديهم تاريخ من الحساسية الشديدة أو الربو.
ينبغي تجنب الولادة عن طريق الوريد أو داخل الشرايين، وكذلك الحقن في أو بالقرب من الأعصاب الطرفية الرئيسية أو شرايين الدم، لأنها يمكن أن تسبب إصابة الأوعية الدموية العصبية.
Side-effects
- كما هو الحال مع البنسلينات الأخرى، من المحتمل أن تحدث تفاعلات غير مرغوب فيها لظاهرة الحساسية، خاصة في الأفراد الذين أظهروا سابقًا فرط الحساسية للبنسلينات أو في أولئك الذين لديهم تاريخ من الحساسية أو الربو أو حمى القش أو الشرى. تم الإبلاغ عن ما يلي مع البنسلين G بالحقن: عام: تفاعلات فرط الحساسية بما في ذلك ما يلي: الطفح الجلدي (التهاب الجلد البقعي الحطاطي إلى التقشري)، الشرى، الوذمة الحنجرية، الحمى، كثرة اليوزينيات؛ تفاعلات أخرى شبيهة بداء المصل (بما في ذلك قشعريرة، حمى، وذمة، ألم مفصلي، وسجود)؛ والحساسية المفرطة بما في ذلك الصدمة والموت. الجهاز الهضمي: التهاب القولون الغشائي الكاذب. قد تظهر أعراض التهاب القولون الغشائي الكاذب أثناء أو بعد العلاج المضاد للبكتيريا.
Drug Interactions
يزيد ويطيل مستويات البنسلين في الدم مع البروبينسيد.
التتراسيكلين قد يقاوم تأثير البنسلين المبيد للجراثيم.
Contraindications
أي تفاعل حساس للبنسلين أو البروكايين في الماضي يعد موانع.
Mode of actions
البكتيريا إيجابية الجرام، والمكورات سلبية الجرام، وبعض البكتيريا الأخرى سالبة الجرام، واللولبيات، والفطريات الشعوية كلها حساسة للبنزيل بنسلين. إنه يثبط تخليق جدار الخلية البكتيرية عن طريق ربط وتثبيط إنزيم الببتيداز على السطح الداخلي لغشاء الخلية البكتيرية، مما يمنع مرحلة الارتباط المتبادل النهائية للتخليق الحيوي للببتيدوغليكان. البنسليناز وغيره من اللاكتاميز هي مثبطات.
يتداخل مع تخليق الببتيدات المخاطية في جدار الخلية أثناء التكاثر النشط، مما يؤدي إلى عمل مبيد للجراثيم ضد البكتيريا الحساسة.
Dosage & Administration
عدوى المكورات العقدية المجموعة أ- عدوى الجهاز التنفسي العلوي والتهابات الجلد والأنسجة الرخوة والحمى القرمزية والحمرة.
يوصى بالجرعات التالية:
المرضى البالغين والأطفال الذين يزيد وزنهم عن 60 رطلاً. في الوزن: 2,400,000 وحدة.
مرضى الأطفال من 30 إلى 60 رطلاً: 900000 وحدة إلى 1200000 وحدة.
مرضى الأطفال أقل من 30 رطلاً: 600000 وحدة.
ملاحظة: يتم عادةً إعطاء العلاج بالجرعة الموصى بها في جلسة واحدة باستخدام مواقع مراسلة فورية متعددة عند الإشارة إليها. يمكن استخدام جدول جرعات بديل، مع إعطاء نصف (1/2) الجرعة الإجمالية في اليوم الأول ونصف (1/2) في اليوم الثالث.
عدوى المكورات الرئوية (باستثناء التهاب السحايا بالمكورات الرئوية)
600000 وحدة لدى مرضى الأطفال و 1200000 وحدة لدى البالغين، تكرر كل يومين أو ثلاثة أيام حتى تعود درجة الحرارة إلى طبيعتها لمدة 48 ساعة. قد تكون أشكال أخرى من البنسلين ضرورية للحالات الشديدة.
Pregnancy & Lactation
على الرغم من أن دراسات التكاثر الحيواني أظهرت تأثيرًا سلبيًا حتى في بعض الأحيان غير قادرة على إثبات المخاطر على الجنين ولا توجد دراسات كافية ومراقبة بشكل جيد عند النساء الحوامل، ولكن أثناء الحمل، يمكن استخدام هذا الدواء فقط عند الحاجة إليه بالتأكيد.
ناقش مع أطبائك وأخبرهم بتعليقاتك حول هذا الدواء.
لا توجد معلومات محددة حول ما إذا كان هذا الدواء ينتقل إلى الطفل عن طريق حليب الثدي. ناقش مع طبيبك قبل الرضاعة الطبيعية.
Pack Size & Price
1 vial pack Price : ৳9.1
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