Pronapen 8 LAC (Injection)
Manufactured by: Renata Limited
Benzyl Penicillin + Procaine Penicillin Similar medicine
Pronapen 8 LAC is indicated for
- Meningitis
- Peritonitis
- Milzbrand
- Nicht-Gonokokken-Urethritis
- Diphtherie
- Syphilis
- Infektionen durch Staphylokokken (anfällige Stämme)
- Streptokokken
- Pneumokokken-Arten Gonorrhoe
- subakute bakterielle Endokarditis
- obere Atemwege
- Erysipel
- Haut- und Weichteilinfektionen
- mittelschwere Lungenentzündung und Mittelohrentzündung
- Empyem
- Bakteriämie
- Perikarditis
- Arthritis
Precautions and warnings
Penicillin sollte bei Personen mit schweren Allergien oder Asthma in der Vorgeschichte mit Vorsicht eingenommen werden.
Eine intravenöse oder intraarterielle Verabreichung sowie Injektionen in oder in die Nähe wichtiger peripherer Nerven oder Blutarterien sollten vermieden werden, da sie neurovaskuläre Schäden verursachen können.
Side-effects
- Wie bei anderen Penicillinen ist es wahrscheinlich
- dass unerwünschte Reaktionen der Überempfindlichkeitsphänomene auftreten
- insbesondere bei Personen
- die zuvor eine Überempfindlichkeit gegen Penicilline gezeigt haben oder bei denen in der Vergangenheit Allergien
- Asthma
- Heuschnupfen oder Urtikaria aufgetreten sind. Folgendes wurde bei parenteraler Gabe von Penicillin G berichtet: Allgemein: Überempfindlichkeitsreaktionen
- einschließlich der folgenden: Hautausschläge (makulopapulöse bis exfoliative Dermatitis)
- Urtikaria
- Kehlkopfödem
- Fieber
- Eosinophilie; andere serumkrankheitsähnliche Reaktionen (einschließlich Schüttelfrost
- Fieber
- Ödeme
- Arthralgie und Erschöpfung); und Anaphylaxie einschließlich Schock und Tod. Gastrointestinal: Pseudomembranöse Kolitis. Während oder nach einer antibakteriellen Behandlung können Symptome einer pseudomembranösen Kolitis auftreten.
Drug Interactions
Erhöht und verlängert den Penicillinspiegel im Serum mit Probenecid.
Tetracyclin kann der bakteriziden Wirkung von Penicillin entgegenwirken.
Contraindications
Eine frühere Penicillin- oder Procain-Überempfindlichkeitsreaktion ist eine Kontraindikation.
Mode of actions
Grampositive Bakterien, gramnegative Kokken, einige andere gramnegative Bakterien, Spirochäten und Actinomyceten sind alle anfällig für Benzylpenicillin. Es hemmt die bakterielle Zellwandsynthese, indem es Transpeptidasen auf der Innenfläche der bakteriellen Zellmembran bindet und inaktiviert und so die letzte Vernetzungsstufe der Peptidoglycan-Biosynthese verhindert. Penicillinase und andere β-Lactamasen sind Inhibitoren.
Beeinträchtigt die Synthese von Mucopeptiden in der Zellwand während der aktiven Vermehrung, was zu einer bakteriziden Wirkung gegen empfindliche Bakterien führt.
Dosage & Administration
Streptokokken-Infektionen der Gruppe A – Infektionen der oberen Atemwege, Haut- und Weichteilinfektionen, Scharlach und Erysipel.
Folgende Dosierungen werden empfohlen:
Erwachsene und pädiatrische Patienten über 60 Pfund. im Gewicht: 2.400.000 Einheiten.
Pädiatrische Patienten von 30 bis 60 Pfund: 900.000 Einheiten bis 1.200.000 Einheiten.
Pädiatrische Patienten unter 30 Pfund: 600.000 Einheiten.
HINWEIS: Die Behandlung mit der empfohlenen Dosierung erfolgt normalerweise in einer einzigen Sitzung und bei Bedarf an mehreren IM-Stellen. Es kann ein alternativer Dosierungsplan verwendet werden, bei dem die Hälfte (1/2) der Gesamtdosis an Tag 1 und die Hälfte (1/2) an Tag 3 verabreicht wird.
Pneumokokken-Infektionen (außer Pneumokokken-Meningitis)
600.000 Einheiten bei pädiatrischen Patienten und 1.200.000 Einheiten bei Erwachsenen, alle 2 oder 3 Tage wiederholt, bis die Temperatur 48 Stunden lang normal ist. In schweren Fällen können andere Formen von Penicillin erforderlich sein.
Pregnancy & Lactation
Obwohl Reproduktionsstudien an Tieren eine schädliche Wirkung gezeigt haben, konnte das Risiko für den Fötus manchmal sogar nicht nachgewiesen werden, und es gibt keine ausreichenden und gut kontrollierten Studien bei schwangeren Frauen. Während der Schwangerschaft kann dieses Arzneimittel jedoch nur dann angewendet werden, wenn dies unbedingt erforderlich ist.
Besprechen Sie dies mit Ihren Ärzten und teilen Sie ihnen Feedback zu diesem Arzneimittel mit.
Es liegen keine spezifischen Informationen darüber vor, ob dieses Arzneimittel über die Muttermilch auf das Baby übertragen wird. Besprechen Sie dies mit Ihrem Arzt, bevor Sie stillen.
Pack Size & Price
1 vial pack Price : ৳9.1
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