Pronapen 8 LAC (Injection)
Manufactured by: Renata Limited
Benzyl Penicillin + Procaine Penicillin Similar medicine
Pronapen 8 LAC is indicated for
- Meningite
- peritonite
- antraz
- uretrite não gonocócica
- difteria
- sífilis
- infecções causadas por estafilococos (cepas sensíveis)
- estreptococos
- gonorreia da espécie Pneumococcus
- endocardite bacteriana subaguda
- trato respiratório superior
- erisipela
- infecções de pele e tecidos moles
- pneumonia e otite média moderadamente graves
- empiema
- bacteremia
- Pericardite
- artrite
Precautions and warnings
A penicilina deve ser tomada com cautela em pessoas com histórico de alergias graves ou asma.
A administração intravenosa ou intra-arterial, bem como injeções nos principais nervos periféricos ou artérias sanguíneas ou próximo a eles, devem ser evitadas porque podem causar lesões neurovasculares.
Side-effects
- Tal como acontece com outras penicilinas
- é provável que ocorram reações indesejáveis dos fenômenos de sensibilidade
- particularmente em indivíduos que demonstraram anteriormente hipersensibilidade às penicilinas ou naqueles com histórico de alergia
- asma
- febre do feno ou urticária. O seguinte foi relatado com penicilina G parenteral: Geral: Reações de hipersensibilidade incluindo as seguintes: erupções cutâneas (dermatite maculopapular a esfoliativa)
- urticária
- edema laríngeo
- febre
- eosinofilia; outras reações semelhantes à doença do soro (incluindo calafrios
- febre
- edema
- artralgia e prostração); e anafilaxia incluindo choque e morte. Gastrointestinal: colite pseudomembranosa. O início dos sintomas da colite pseudomembranosa pode ocorrer durante ou após o tratamento antibacteriano.
Drug Interactions
Aumenta e prolonga os níveis séricos de penicilina com probenecida.
A tetraciclina pode neutralizar o efeito bactericida da penicilina.
Contraindications
Qualquer reação de hipersensibilidade à penicilina ou procaína no passado é uma contra-indicação.
Mode of actions
Bactérias Gram-positivas, cocos Gram-negativos, algumas outras bactérias Gram-negativas, espiroquetas e actinomicetos são todas suscetíveis à benzilpenicilina. Inibe a síntese da parede celular bacteriana ligando-se e inativando as transpeptidases na superfície interna da membrana celular bacteriana, evitando o estágio final de reticulação da biossíntese do peptidoglicano. A penicilinase e outras?-lactamases são inibidores.
Interfere na síntese de mucopeptídeos na parede celular durante a multiplicação ativa, resultando em ação bactericida contra bactérias sensíveis.
Dosage & Administration
Infecções estreptocócicas Grupo A – Infecções do trato respiratório superior, infecções da pele e dos tecidos moles, escarlatina e erisipela.
As seguintes doses são recomendadas:
Adultos e pacientes pediátricos com mais de 60 libras. em peso: 2.400.000 unidades.
Pacientes pediátricos de 30 a 60 libras: 900.000 unidades a 1.200.000 unidades.
Pacientes pediátricos com menos de 30 libras: 600.000 unidades.
NOTA: O tratamento com a dosagem recomendada geralmente é administrado em uma única sessão usando vários locais IM, quando indicado. Um esquema posológico alternativo pode ser usado, administrando metade (1/2) da dose total no dia 1 e metade (1/2) no dia 3.
Infecções pneumocócicas (exceto meningite pneumocócica)
600.000 unidades em pacientes pediátricos e 1.200.000 unidades em adultos, repetidas a cada 2 ou 3 dias até a temperatura normalizar por 48 horas. Outras formas de penicilina podem ser necessárias em casos graves.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso, mesmo por vezes incapaz de demonstrar o risco para o feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário.
Discuta com seus médicos e dê-lhes comentários sobre este medicamento.
Não há informações específicas sobre se este medicamento é transmitido ao bebê através do leite materno. Discuta com seu médico antes de amamentar.
Pack Size & Price
1 vial pack Price : ৳9.1
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